David N Arnosti

The Arnosti laboratory studies gene regulation in the context of development. A main focus of our laboratory’s research has been understanding the “cis regulatory grammar” by which combinations of transcription factor binding sites in regulatory regions provide precise outputs for genes regulated in tissue- and temporal-specific patterns. A second related area concerns transcriptional repressors and corepressors, which are key contributors to this regulation. Our research has provided novel insights into biochemical and genetic pathways regulated by these factors. The powerful genetics and molecular biology of Drosophila allows us to test the importance of cis- and trans-acting regulators of transcription in a developmental setting. This fundamental research is critical for understanding the central regulatory mechanisms in biology, including in development, disease, and evolution.

# Titles
* Professor

# Education
* Ph.D. 1989, University of California, Berkeley
* B.A. 1982, Lawrence University, Appleton, WI

# Previous Appointments
* 1993-96, UC San Diego
* 1990-92, University of Zurich, Switzerland

# Links
* [Arnosti Laboratory News](https://arnostilab.natsci.msu.edu/lab-news/index.aspx)
* [Arnosti Laboratory Website](https://arnostilab.natsci.msu.edu/)
* [Current Research](https://arnostilab.natsci.msu.edu/research/index.aspx)
* [Recent Publications](https://arnostilab.natsci.msu.edu/publications/index.aspx)
* [Google Scholar Citations](https://scholar.google.com/citations?user=yCdoo65q6NMC&hl=en&oi=ao)