Shannon Manning

My laboratory studies the molecular epidemiology and evolutionary genetics of infectious diseases, namely those caused by diarrheagenic Escherichia coli and Streptococcus agalactiae. We apply molecular biology, epidemiological and evolutionary methods to answer questions about pathogenesis, emergence, virulence, evolution, and transmission of pathogens in human and animal populations. Our studies of both Shiga toxin-producing E. coli (STEC) O157:H7 and S. agalactiae are similar in that the phylogenetic analysis of genomic data and the subsequent epidemiological analysis identified specific strain types to be more important for disease. Most of our current and future research projects are associated with these key findings that will ultimately enhance our understanding of how genetic variation contributes to clinical illness.

We also manage and curate the STEC Center, which serves as a repository for STEC and other enteric pathogens.

For additional information, please go to the Manning lab site

###Education
MSU Foundation Professor
M.P.H. (1998) Hospital and Molecular Epidemiology, University of Michigan, Ann Arbor, Mich.
Ph.D. (2001) Molecular Epidemiology, University of Michigan, Ann Arbor, Mich.
Postdoctoral studies:
Emerging Infectious Disease Fellowship CDC/APHL 2001-2004
University of Michigan, 2001-2002
Michigan State University, 2004-2010