Shannon Manning

We study the genomic epidemiology and evolution of infectious diseases, namely those caused by diarrheagenic Escherichia coli and group B Streptococcus (GBS). We use 'omics tools as well as microbiology and molecular biology methods to answer questions about pathogenesis, emergence, virulence, evolution, and transmission of pathogens in human and animal populations. Our studies of both Shiga toxin-producing E. coli (STEC) O157:H7 and GBS are similar in that the genomic and epidemiological analyses uncovered specific strain types to be more important for disease. Most of our current and future research projects are associated with these key findings that can enhance our understanding of how genetic variation contributes to clinical illness. In addition, some of our recent studies have focused on determining how antibiotics and other perturbations impact the gut microbiome. 

###Education
MSU Research Foundation Distinguished Professor
M.P.H. (1998) Hospital and Molecular Epidemiology, University of Michigan, Ann Arbor, Mich.
Ph.D. (2001) Molecular Epidemiology, University of Michigan, Ann Arbor, Mich.
Postdoctoral studies:
Emerging Infectious Disease Fellowship CDC/APHL 2001-2004
University of Michigan, 2001-2002
Michigan State University, 2004-2010